JOURNAL ARTICLE
LINC01232 promotes lung squamous cell carcinoma progression through modulating miR-181a-5p/SMAD2 axis
Dongliang ZhangMinglei HuaNan Zhang
Year: 2022 Journal: The American Journal of the Medical Sciences Vol: 365 (4)Pages: 386-395 Publisher: Elsevier BV
Abstract
In summary, our study demonstrates that LINC01232 expression increases in LUSC tissues and cell lines and promotes LUSC progression by modulating the miR-181a-5p/SMAD2 signaling, providing new potential drug targets for LUSC treatment.
Keywords:
Vimentin Gene silencing Cell growth Cancer research Gene knockdown Medicine Downregulation and upregulation Cell migration Carcinogenesis Tumor progression Small interfering RNA Biology Cell culture A549 cell Western blot Cell biology Transfection Pathology Internal medicine Lung cancer Cancer Immunohistochemistry
Metrics
3
Cited By
0.41
FWCI (Field Weighted Citation Impact)
51
Refs
0.51
Citation Normalized Percentile
Is in top 1%
Is in top 10%
Citation History
Topics
Cancer-related molecular mechanisms research
Life Sciences → Biochemistry, Genetics and Molecular Biology → Cancer Research
Circular RNAs in diseases
Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology
MicroRNA in disease regulation
Life Sciences → Biochemistry, Genetics and Molecular Biology → Cancer Research
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