Practicing sustainable chemistry is one of the best ways to address ‘man-made’ environmental perils. The decorum set by the laws of green chemistry can lead us towards mitigating such menace. Multi-component reactions are one such weapon in the armoury of a chemist towards developing and inventing commodities ranging from life-saving drugs to lifestyle products through sustainable synthetic methodologies. Though much advancement is accomplished in developing such reactions, a correlation between ‘environmentally benign operation’ and ‘mere synthesis’ is yet to be realized. Herein, we have tried to highlight the gradual advancement of this procedure and what still needs to be achieved to entice the philosopher within ourselves towards greener thoughts and ideas.
Stefano ProttiAndrea BassoSilvia Garbarino
Hon Loong LamBing Shen HowBoon Hooi Hong