Salicylic acid-based hypoxia-responsive chemodynamic nanomedicines boost antitumor immunotherapy by modulating immunosuppressive tumor microenvironment

Kai Sun; Jiaying Yu; Jinzhong Hu; Jian Chen; Jia Song; Zhixin Chen; Zhuoer Cai; Zhuoxuan Lu; Liming Zhang; Zhifei Wang

doi:10.1016/j.actbio.2022.06.026

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Salicylic acid-based hypoxia-responsive chemodynamic nanomedicines boost antitumor immunotherapy by modulating immunosuppressive tumor microenvironment

Kai Sun Jiaying Yu Jinzhong Hu Jian Chen Jia Song Zhixin Chen Zhuoer Cai Zhuoxuan Lu Liming Zhang Zhifei Wang

Year: 2022 Journal: Acta Biomaterialia Vol: 148 Pages: 230-243 Publisher: Elsevier BV

DOI: 10.1016/j.actbio.2022.06.026

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Keywords:

Tumor microenvironment Cancer research Salicylic acid Immunotherapy Hypoxia (environmental) Cytotoxicity Immune system Materials science Medicine Tumor cells Immunology Chemistry In vitro

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Nanoplatforms for cancer theranostics

Physical Sciences → Engineering → Biomedical Engineering

Immune cells in cancer

Life Sciences → Immunology and Microbiology → Immunology

Nanoparticle-Based Drug Delivery

Physical Sciences → Materials Science → Biomaterials

Salicylic acid-based hypoxia-responsive chemodynamic nanomedicines boost antitumor immunotherapy by modulating immunosuppressive tumor microenvironment

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