Preparation, characterization, and in vitro release of folic acid-conjugated chitosan nanoparticles loaded with methotrexate for targeted delivery

Jingou Ji; Danjun Wu; Li Liu; Jida Chen; Yi Xu

doi:10.1007/s00289-011-0674-x

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Preparation, characterization, and in vitro release of folic acid-conjugated chitosan nanoparticles loaded with methotrexate for targeted delivery

Jingou Ji Danjun Wu Li Liu Jida Chen Yi Xu

Year: 2011 Journal: Polymer Bulletin Vol: 68 (6)Pages: 1707-1720 Publisher: Springer Science+Business Media

DOI: 10.1007/s00289-011-0674-x

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Keywords:

Chitosan Nanoparticle Nuclear chemistry Fourier transform infrared spectroscopy Conjugated system Chemistry Drug delivery Conjugate Drug carrier Particle size Covalent bond Controlled release Organic chemistry Materials science Nanotechnology Chemical engineering Polymer Physical chemistry

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Advanced Drug Delivery Systems

Life Sciences → Pharmacology, Toxicology and Pharmaceutics → Pharmaceutical Science

Pregnancy and Medication Impact

Health Sciences → Medicine → Public Health, Environmental and Occupational Health

Chronic Myeloid Leukemia Treatments

Health Sciences → Medicine → Hematology

Preparation, characterization, and in vitro release of folic acid-conjugated chitosan nanoparticles loaded with methotrexate for targeted delivery

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