Nanostructured Metal Organic Framework Modified Glassy Carbon Electrode as a High Efficient Non-Enzymatic Amperometric Sensor for Electrochemical Detection of H2O2

Abstract

Metal-organic frameworks have recently been considered very promising modifiers in electrochemical analysis due to their unique characteristics among which tunable pore sizes, crystalline ordered structures, large surface areas and chemical tenability are worth noting. In the present research, Cu(btec)0.5DMF was electrodeposited on the surface of glassy carbon electrode at room temperature under cathodic potential and was initially used as the active materials for the detection of H2O2. The cyclic voltammogram of Cu(btec)0.5DMF modified GC electrode shows distinct redox peaks potentials at +0.002 and +0.212 V in 0.1 M phosphate buffer solution (pH 6.5) corresponding to Cu(II)/Cu(I) in Cu(btec)0.5DMF. Acting as the electrode materials of a non-enzymatic H2O2 biosensor, the Cu(btec)0.5DMF brings about a promising electrocatalytic performance. The high electrocatalytic activity of the Cu(btec)0.5DMF modified GC electrode is demonstrated by the amperometric response towards H2O2 reduction with a wide linear range from 5 μM to 8000 μM, a low detection limit of 0.865 μM, good stability and high selectivity at an applied potential of −0.2 V, which was higher than some H2O2 biosensors. Keywords: MOF, Electrochemical, Biosensor, Amperometry