Absolute calibration of multi-sensor fluorescence probes for interstitial photodynamic therapy monitoring

Abstract

Fluorescent multi-sensor fiber-optic probes for spatially resolved monitoring of Interstitial Photodynamic Therapy were absolute calibrated using an integrating cylinder. The dynamic response was evaluated and showed linear responsivity in the test range from 1 – 60 mW·cm−2. Sensor-probe and optoelectronic readout provides a accuracy of better than 10%.