A Novel Three-Dimensional Hydrogel-Based Microarray Platform

Abstract

Three dimensional (3D) microarrays utilizing hydrogel matrixes are becoming increasingly attractive as a desired format for bio-analysis. These materials offer significant advantages as a scaffolding for capture agents over more conventional two dimensional (2D) printed formats in both captures per site and the ability to provide an environment more closely resembling that of a free solution. Biocept has developed a flexible three dimensional polyethylene glycol (PEG) polymer based platform suitable for a variety of biological assays. This novel approach is simple, biocompatible and provides a high degree of reproducibility and very low variability in the final array.