Upregulation of cytosolic NADP+-dependent isocitrate dehydrogenase by hyperglycemia protects renal cells against oxidative stress

Soh-Hyun Lee; Sun-Ok Ha; Ho‐Jin Koh; Kil‐Soo Kim; Seon-Min Jeon; Myung‐Sook Choi; Oh‐Shin Kwon; Tae‐Lin Huh

doi:10.1007/s10059-010-0012-4

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Upregulation of cytosolic NADP+-dependent isocitrate dehydrogenase by hyperglycemia protects renal cells against oxidative stress

Soh-Hyun Lee Sun-Ok Ha Ho‐Jin Koh Kil‐Soo Kim Seon-Min Jeon Myung‐Sook Choi Oh‐Shin Kwon Tae‐Lin Huh

Year: 2009 Journal: Molecules and Cells Publisher: Springer Science+Business Media

DOI: 10.1007/s10059-010-0012-4

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Keywords:

Oxidative stress Downregulation and upregulation Isocitrate dehydrogenase Reactive oxygen species Glutathione Cytosol Chemistry Antioxidant Diabetic nephropathy Endocrinology Nephropathy Cancer research Internal medicine Kidney Biochemistry Diabetes mellitus Biology Medicine Enzyme

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Advanced Glycation End Products research

Life Sciences → Biochemistry, Genetics and Molecular Biology → Clinical Biochemistry

Chronic Kidney Disease and Diabetes

Health Sciences → Medicine → Nephrology

Aldose Reductase and Taurine

Life Sciences → Biochemistry, Genetics and Molecular Biology → Cell Biology

Upregulation of cytosolic NADP+-dependent isocitrate dehydrogenase by hyperglycemia protects renal cells against oxidative stress

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