Synergistic checkpoint-blockade and radiotherapy–radiodynamic therapy via an immunomodulatory nanoscale metal–organic framework

Kaiyuan Ni; Ziwan Xu; August Culbert; Taokun Luo; Nining Guo; Kaiting Yang; Erik Pearson; Ben Preusser; Tong Wu; Patrick J. La Rivière; Ralph R. Weichselbaum; Michael T. Spiotto; Wenbin Lin

doi:10.1038/s41551-022-00846-w

JOURNAL ARTICLE

Synergistic checkpoint-blockade and radiotherapy–radiodynamic therapy via an immunomodulatory nanoscale metal–organic framework

Kaiyuan Ni Ziwan Xu August Culbert Taokun Luo Nining Guo Kaiting Yang Erik Pearson Ben Preusser Tong Wu Patrick J. La Rivière Ralph R. Weichselbaum Michael T. Spiotto Wenbin Lin

Year: 2022 Journal: Nature Biomedical Engineering Vol: 6 (2)Pages: 144-156 Publisher: Nature Portfolio

DOI: 10.1038/s41551-022-00846-w

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Keywords:

Blockade Radiation therapy Nanoscopic scale Metal-organic framework Medicine Chemistry Cancer research Nanotechnology Materials science Internal medicine Receptor

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Nanoplatforms for cancer theranostics

Physical Sciences → Engineering → Biomedical Engineering

Metal-Organic Frameworks: Synthesis and Applications

Physical Sciences → Chemistry → Inorganic Chemistry

Nanoparticle-Based Drug Delivery

Physical Sciences → Materials Science → Biomaterials

Synergistic checkpoint-blockade and radiotherapy–radiodynamic therapy via an immunomodulatory nanoscale metal–organic framework

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