Patient-derived xenograft models capture genomic heterogeneity in endometrial cancer

Vanessa Bonazzi; Olga Kondrashova; Deborah S. Smith; Kátia Nones; Asmerom T. Sengal; Robert J. Ju; Leisl Packer; Lambros T. Koufariotis; Stephen H. Kazakoff; Aimee L. Davidson; Priya Ramarao-Milne; Vanessa Lakis; Felicity Newell; Rebecca F. Rogers; Claire M. Davies; James Nicklin; Andrea Garrett; Naven Chetty; Lewis Perrin; John V. Pearson; Ann‐Marie Patch; Nicola Waddell; Pamela M. Pollock

doi:10.1186/s13073-021-00990-z

JOURNAL ARTICLE

Patient-derived xenograft models capture genomic heterogeneity in endometrial cancer

Vanessa Bonazzi Olga Kondrashova Deborah S. Smith Kátia Nones Asmerom T. Sengal Robert J. Ju Leisl Packer Lambros T. Koufariotis Stephen H. Kazakoff Aimee L. Davidson Priya Ramarao-Milne Vanessa Lakis Felicity Newell Rebecca F. Rogers Claire M. Davies James Nicklin Andrea Garrett Naven Chetty Lewis Perrin John V. Pearson Ann‐Marie Patch Nicola Waddell Pamela M. Pollock

Year: 2022 Journal: Genome Medicine Vol: 14 (1)Pages: 3-3 Publisher: BioMed Central

DOI: 10.1186/s13073-021-00990-z

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Keywords:

Copy number analysis Cancer Cancer research Exome sequencing Somatic evolution in cancer Biology Exome Medicine Endometrial cancer Copy-number variation Mutation Gene Internal medicine Genetics Genome

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Endometrial and Cervical Cancer Treatments

Health Sciences → Medicine → Obstetrics and Gynecology

Ovarian cancer diagnosis and treatment

Health Sciences → Medicine → Reproductive Medicine

Cancer Genomics and Diagnostics

Life Sciences → Biochemistry, Genetics and Molecular Biology → Cancer Research

Patient-derived xenograft models capture genomic heterogeneity in endometrial cancer

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Abstract PR009: Characterization of patient-derived xenograft models of endometrial cancer