Stimuli-responsive nano vehicle enhances cancer immunotherapy by coordinating mitochondria-targeted immunogenic cell death and PD-L1 blockade

Qiuyi Li; Cheng Chen; Jinxia Kong; Lian Li; Junlin Li; Yuan Huang

doi:10.1016/j.apsb.2021.11.005

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Stimuli-responsive nano vehicle enhances cancer immunotherapy by coordinating mitochondria-targeted immunogenic cell death and PD-L1 blockade

Qiuyi Li Cheng Chen Jinxia Kong Lian Li Junlin Li Yuan Huang

Year: 2021 Journal: Acta Pharmaceutica Sinica B Vol: 12 (5)Pages: 2533-2549 Publisher: Elsevier BV

DOI: 10.1016/j.apsb.2021.11.005

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Keywords:

Calreticulin Immunogenic cell death Mitochondrion Blockade Cancer immunotherapy Immune system Programmed cell death Cancer research Reactive oxygen species Mitochondrial ROS Immunotherapy Endoplasmic reticulum Downregulation and upregulation Chemistry Apoptosis Cell biology Immunology Biology Receptor Biochemistry

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Nanoplatforms for cancer theranostics

Physical Sciences → Engineering → Biomedical Engineering

Cancer Research and Treatments

Life Sciences → Biochemistry, Genetics and Molecular Biology → Biotechnology

Autophagy in Disease and Therapy

Health Sciences → Medicine → Epidemiology

Stimuli-responsive nano vehicle enhances cancer immunotherapy by coordinating mitochondria-targeted immunogenic cell death and PD-L1 blockade

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