Enrique Fernández-Vivancos González
Molecular recognition involving glycoprotein-mediated interactions is ubiquitous in both normal and pathological natural processes. Therefore, visualization of these interactions and the extent of expression of the sugars is a challenge in medical diagnosis, monitoring of therapy, and drug design. Here, we review the literature on the development and validation of probes for magnetic resonance imaging using carbohydrates either as targeting vectors or as a target. Lectins are important targeting vectors for carbohydrate end groups, whereas selectins, the asialoglycoprotein receptor, sialic acid end groups, hyaluronic acid, and glycated serum and hemoglobin are interesting carbohydrate targets.
Antonio Fernández EscobarFernando García López
Daniel Ascorbe MartínezIñigo GraciaIgnacio Yoldi DiosdadoNéstor Tenés
Angel Carrero y del PozoJesús Angel Duque ChascoDavid Pérez AlonsoRubén Pérez Alonso