Mixed Ligand Oxovanadium (IV) Complexes of 5,6-Dimethyl-1,10-phenanthroline and Amino Acid Schiff Bases Containing Salicylaldehyde: Synthesis and Characterization with Antibacterial Properties

Abstract

<p>Five new oxovanadium (IV) complexes have been synthesized from two mixed ligand, 5,6-Dimethyl-1,10-phenanthroline and amino acid derived Schiff bases containing salicylaldehyde. All the synthesized complexes were characterized by some physicochemical properties, molar conductance, magnetic  susceptibilities measurements, elemental analysis, UV-Visible and IR spectral studies. The molar conductance values reveal the non-electrolytic nature of the complexes. The magnetic moment values indicate that the complexes are paramagnetic in nature. IR spectral data indicates the coordination of tridentate amino acid Schiff base ligands to the vanadyl (VO2+) ion through O, N, Odonor. ESI-MS spectral data confirms the proposed molecular formula of the complexes. All the analytical data suggested that all the complexes possess to have distorted octahedral geometry. Antibacterial activity of the complexes was tested against two Gram positive bacteria Escherichia coli and Pseudomonas aeruginosa and two Gram negative bacteria Staphylococcus aureus and Bacillus cereus with Kanamycin (K-30) standard. The result shows that all the complexes possess to have moderate to strong potential antibacterial activity against all the tested pathogenic bacteria.</p>