ORMDL3 regulates cigarette smoke–induced endoplasmic reticulum stress in airway smooth muscle cells

Rui Chen; Charalambos Michaeloudes; Yingmin Liang; Pankaj Bhavsar; Kian Fan Chung; Msm Ip; Jcw Mak

doi:10.1016/j.jaci.2021.09.028

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ORMDL3 regulates cigarette smoke–induced endoplasmic reticulum stress in airway smooth muscle cells

Rui Chen Charalambos Michaeloudes Yingmin Liang Pankaj Bhavsar Kian Fan Chung Msm Ip Jcw Mak

Year: 2021 Journal: Journal of Allergy and Clinical Immunology Vol: 149 (4)Pages: 1445-1457.e5 Publisher: Elsevier BV

DOI: 10.1016/j.jaci.2021.09.028

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Keywords:

Unfolded protein response Endoplasmic reticulum Small interfering RNA Gene knockdown COPD Downregulation and upregulation Biology Protein kinase A Endocrinology Internal medicine Inflammation Cell biology Cancer research Kinase Immunology Apoptosis Medicine Biochemistry Transfection

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Endoplasmic Reticulum Stress and Disease

Life Sciences → Biochemistry, Genetics and Molecular Biology → Cell Biology

Autophagy in Disease and Therapy

Health Sciences → Medicine → Epidemiology

Heme Oxygenase-1 and Carbon Monoxide

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

ORMDL3 regulates cigarette smoke–induced endoplasmic reticulum stress in airway smooth muscle cells

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