JOURNAL ARTICLE

A light and hypoxia-activated nanodrug for cascade photodynamic-chemo cancer therapy

Yin ZhongSi HuangChujie ZhengJinsheng HuangBo LiShisong HanHong XiaoYong WangXintao Shuai

Year: 2021 Journal:   Biomaterials Science Vol: 9 (15)Pages: 5218-5226   Publisher: Royal Society of Chemistry

Abstract

A pH-sensitive polymeric nanovesicle is prepared to co-encapsulate Ce6 and tirapazamine (TPZ) as a light and hypoxia-activated nanodrug for highly efficient photodynamic-chemo cancer therapy.

Keywords:
Tirapazamine Photodynamic therapy Hypoxia (environmental) Cancer therapy Chemistry Photosensitizer Cancer research Tumor hypoxia Cancer Photochemistry Medicine Radiation therapy Biochemistry Internal medicine In vitro Oxygen Cytotoxicity Organic chemistry

Metrics

18
Cited By
1.48
FWCI (Field Weighted Citation Impact)
34
Refs
0.78
Citation Normalized Percentile
Is in top 1%
Is in top 10%

Citation History

Topics

Nanoplatforms for cancer theranostics
Physical Sciences →  Engineering →  Biomedical Engineering
Photodynamic Therapy Research Studies
Health Sciences →  Medicine →  Pulmonary and Respiratory Medicine
Advanced Nanomaterials in Catalysis
Physical Sciences →  Materials Science →  Materials Chemistry

Related Documents

© 2026 ScienceGate Book Chapters — All rights reserved.