Ligustroflavone ameliorates CCl4-induced liver fibrosis through down-regulating the TGF-β/Smad signaling pathway

Rong Kang; Wen Tian; Wei Cao; Yang Sun; Huinan Zhang; Ying-Da Feng; Chen Li; Zezhi Li; Xiaoqiang Li

doi:10.1016/s1875-5364(21)60018-3

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Ligustroflavone ameliorates CCl4-induced liver fibrosis through down-regulating the TGF-β/Smad signaling pathway

Rong Kang Wen Tian Wei Cao Yang Sun Huinan Zhang Ying-Da Feng Chen Li Zezhi Li Xiaoqiang Li

Year: 2021 Journal: Chinese Journal of Natural Medicines Vol: 19 (3)Pages: 170-180 Publisher: Elsevier BV

DOI: 10.1016/s1875-5364(21)60018-3

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Keywords:

Hepatic stellate cell CCL4 Carbon tetrachloride In vivo Fibrosis SMAD Chemistry Western blot Hepatic fibrosis Downregulation and upregulation Liver injury Extracellular matrix Endocrinology Internal medicine Transforming growth factor Medicine Biology Biochemistry

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Liver physiology and pathology

Health Sciences → Medicine → Hepatology

Liver Disease Diagnosis and Treatment

Health Sciences → Medicine → Epidemiology

TGF-β signaling in diseases

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

Ligustroflavone ameliorates CCl4-induced liver fibrosis through down-regulating the TGF-β/Smad signaling pathway

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