JOURNAL ARTICLE

Deformable liposomal codelivery of vorinostat and simvastatin promotes antitumor responses through remodeling tumor microenvironment

Abstract

A deformable liposome system are developed for codelivery of vorinostat and simvastatin for remodeling the TME and for epigenetic combination therapy of non-small cell lung cancer (NSCLC).

Keywords:
Vorinostat Simvastatin Cancer research Tumor microenvironment Liposome Lung cancer Epigenetics Histone deacetylase inhibitor Colchicine Chemistry Medicine Pharmacology Histone deacetylase Histone Oncology Tumor cells Internal medicine Biochemistry

Metrics

24
Cited By
1.01
FWCI (Field Weighted Citation Impact)
55
Refs
0.76
Citation Normalized Percentile
Is in top 1%
Is in top 10%

Citation History

Topics

Peptidase Inhibition and Analysis
Health Sciences →  Medicine →  Oncology
Ubiquitin and proteasome pathways
Life Sciences →  Biochemistry, Genetics and Molecular Biology →  Molecular Biology
Glycosylation and Glycoproteins Research
Life Sciences →  Biochemistry, Genetics and Molecular Biology →  Molecular Biology

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