A study on the viscoelastic behavior of chitosan-polyvinyl alcohol-graphene oxide nanocomposite films as a wound dressing

Abstract

The nanocomposites of Chitosan (CS)-poly vinyl alcohol (PVA) reinforced with graphene oxide (GO) were fabricated by casting in a mold. The nanocomposite films were characterized by various techniques. The viscoelastic properties of the wound dressings were evaluated by dynamic mechanical thermal analysis (DMTA) since the healing quality of a wound dressing depends on such properties. DMTA results also were modeled by the Cole-Cole diagram. Finally, the effects of GO on antimicrobial and biological properties of films were studied. It has been shown that nanocomposite films support the initial attachment, proliferation, and growth of mouse fibroblast cells.