JOURNAL ARTICLE

<p>Guiding Appropriate Timing of Laser Irradiation by Polymeric Micelles for Maximizing Chemo-Photodynamic Therapy</p>

Yun ZhuFangying YuYanan TanLijuan WenYinghong LiHong YuanFuqiang Hu

Year: 2020 Journal:   International Journal of Nanomedicine Vol: Volume 15 Pages: 6531-6543   Publisher: Dove Medical Press

Abstract

In summary, we prepared homoFRET-based theranostic nano-agent (Ce6-CSPD/DOX) for monitoring PDT precisely and decreasing phototoxicity to normal organs before reaching target region. Under the guidance of dynamic fluorescence intensity, the appropriate laser irradiation timing could be monitored to maximize antitumor therapy efficacy, which offered opportunities for monitoring efficiency of chemo-photodynamic therapy in a timely and accurate manner.

Keywords:
Phototoxicity Photodynamic therapy Photosensitizer In vivo Biophysics Fluorescence Doxorubicin Irradiation Glutathione Chemistry Materials science Photochemistry In vitro Medicine Biochemistry Organic chemistry Chemotherapy Biology Surgery Optics

Metrics

15
Cited By
1.24
FWCI (Field Weighted Citation Impact)
30
Refs
0.80
Citation Normalized Percentile
Is in top 1%
Is in top 10%

Citation History

Topics

Photodynamic Therapy Research Studies
Health Sciences →  Medicine →  Pulmonary and Respiratory Medicine
Nanoplatforms for cancer theranostics
Physical Sciences →  Engineering →  Biomedical Engineering
Photoacoustic and Ultrasonic Imaging
Physical Sciences →  Engineering →  Biomedical Engineering

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