JOURNAL ARTICLE

Polyelectrolyte stiffness on gold nanorods mediates cell membrane damage

Nurul ‘Ain AzmanL. BekaleThanh X. NguyenJames Chen Yong Kah

Year: 2020 Journal:   Nanoscale Vol: 12 (26)Pages: 14021-14036   Publisher: Royal Society of Chemistry

Abstract

CGMD showed that ligand mechanical stability which resulted in the exposure of the hydrophobic AuNR core, disrupted the lipid bilayer organization. The damage was confirmed using hemolysis assay whereby lipid bilayer disruption resulted in the release of hemoglobin.

Keywords:
Lipid bilayer Hemolysis Nanorod Membrane Polyelectrolyte Bilayer Biophysics Hemoglobin Stiffness Chemistry Cell membrane Materials science Nanotechnology Biochemistry Composite material Organic chemistry Biology Polymer

Metrics

16
Cited By
1.23
FWCI (Field Weighted Citation Impact)
94
Refs
0.76
Citation Normalized Percentile
Is in top 1%
Is in top 10%

Citation History

Topics

Polymer Surface Interaction Studies
Physical Sciences →  Materials Science →  Surfaces, Coatings and Films
Gold and Silver Nanoparticles Synthesis and Applications
Physical Sciences →  Materials Science →  Electronic, Optical and Magnetic Materials
Nanoparticle-Based Drug Delivery
Physical Sciences →  Materials Science →  Biomaterials
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