Histopathologicalregression after preoperative chemoradiotherapy in locally advanced rectal carcinoma

Abstract

：Neoadjuvantchemoradiotherapy (CRT) has become a standard treatment of locally advanced rectalcarcinomas. There is a close correlation between histopathological regression afterpreoperative CRT and prognosis. To identify the markers for histopathological regressionis significant for clinical treatment. Different strategies of chemoradiotherapy,application of targeted drugs in neoadjuvant chemothercepy and internal from neoodjuvantto operation are correlated with histopathological regression.