JOURNAL ARTICLE
PPARγ参与免疫作用的研究进展
Year: 2004 Journal: Foreign Medical Sciences Section of Immunology Vol: 27 (05)Pages: 291-293
Abstract
过氧化物酶体增殖物激活受体(peroxisome proliferator-activated receptor,PPAR)属于核激素受体超家族,由3个成员组成:PPARα、PPARβ和PPARγ,合成前列腺途径中的代谢产物及格列酮类物质是PPAR-γ的配体.前列腺素的前体来自于饮食中的脂肪酸,对免疫功能有调节作用.PPARγ及其配体参与了1型、2型T细胞及NK细胞的发育、分化,对免疫及炎症反应有重要的调节作用。
Keywords:
Chemistry
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Topics
Peroxisome Proliferator-Activated Receptors
Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology
Inflammatory mediators and NSAID effects
Health Sciences → Medicine → Pharmacology
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