Skin Adnexal Tumors: A Histopathological analysis of 30 Cases at a Tertiary Care Centre

Abstract

Background: Diagnostic challenges are associated with skin adnexal tumors because of a broad spectrum of tumor and tumor-like lesions along with their histological variants, the degree of differentiation, the rare incidence of few of these tumors, and the complex nomenclature.The aim of this study is to study the spectrum and microscopic features of Skin adnexal tumors.Methods: A prospective study was conducted over a period of 2 years from August 2017 to July 2019 in the Department of Pathology, Narayana Medical College and Hospital, Nellore.Formalin fixed, paraffin embedded tissue sections were stained with Hematoxylin and Eosin.Result: Out of the total 30 cases diagnosed as Skin adnexal tumors, 15 (50%) tumors were showing Eccrine differentiation followed by tumors with Pilar differentiation, 8 (26.67%),Apocrine differentiation, 5 (16.67%) and Sebaceous differentiation, 2 (6.66%).The age ranged from 13 to 73 years and male to female ratio was 1.14:1.Most of the tumors were benign, 29 cases (96.67%) while only 1 case (3.33%) was malignant.Clear Cell Hidradenoma was the most common tumor.Conclusion: Morphological features and identifying the path of differentiation are of great importance in diagnosing Skin adnexal tumors.