<scp>l</scp>-Arginine/<scp>l</scp>-lysine functionalized chitosan–casein core–shell and pH-responsive nanoparticles: fabrication, characterization and bioavailability enhancement of hydrophobic and hydrophilic bioactive compounds

Zhiyang Du; Jingbo Liu; Hui Zhang; Yuelin Chen; Xinling Wu; Yanqun Zhang; Xinyu Li; Ting Zhang; Hang Xiao; Boqun Liu

doi:10.1039/d0fo00005a

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l-Arginine/l-lysine functionalized chitosan–casein core–shell and pH-responsive nanoparticles: fabrication, characterization and bioavailability enhancement of hydrophobic and hydrophilic bioactive compounds

Zhiyang Du Jingbo Liu Hui Zhang Yuelin Chen Xinling Wu Yanqun Zhang Xinyu Li Ting Zhang Hang Xiao Boqun Liu

Year: 2020 Journal: Food & Function Vol: 11 (5)Pages: 4638-4647 Publisher: Royal Society of Chemistry

DOI: 10.1039/d0fo00005a

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Abstract

This study developed novel oral delivery systems for the encapsulation, protection, and controlled release of hydrophobic and hydrophilic bioactive compounds based onl-arginine- orl-lysine-functionalized chitosan–casein nanoparticles.

Keywords:

Chitosan Chemistry Bioavailability Lysine Casein Arginine Nanoparticle Biochemistry Amino acid Nanotechnology Materials science

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Proteins in Food Systems

Life Sciences → Agricultural and Biological Sciences → Food Science

Protein Hydrolysis and Bioactive Peptides

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

Advanced Drug Delivery Systems

Life Sciences → Pharmacology, Toxicology and Pharmaceutics → Pharmaceutical Science

l-Arginine/l-lysine functionalized chitosan–casein core–shell and pH-responsive nanoparticles: fabrication, characterization and bioavailability enhancement of hydrophobic and hydrophilic bioactive compounds

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