Electrochemical investigation of dopamine in presence of Uric acid and ascorbic acid at poly (Reactive Blue) modified carbon paste electrode: A voltammetric study

Abstract

The Poly (Reactive Blue) modified carbon paste electrode (MCPE) exhibited good stable and sensitive current responses towards the determination of dopamine (DA) in phosphate buffer solution (PBS pH 7.4). The various parameters like the effect of scan rate, pH and concentration of DA studied. The electrode process was found to be adsorption-controlled and the limit of detection (LOD) of DA obtained to be 4.64 μM. The simultaneous determination of DA in the presence of Ascorbic acid (AA) and Uric acid (UA) was investigated by using cyclic voltammetry (CV). The application of the developed electrode was demonstrated by detecting DA in injection sample with satisfactory recoveries. The sensor was stable, sensitive, selective and reproducible.