JOURNAL ARTICLE
Chimeric-antigen receptor T (CAR-T) cell therapy for solid tumor
Year: 2020 Journal: IOP Conference Series Materials Science and Engineering Vol: 768 (5)Pages: 052051-052051 Publisher: IOP Publishing
Abstract
Abstract Chimeric-antigen receptor T (CAR-T) cell therapy has been researched in the clinical. However, CAR-T cell therapy for solid tumor is faced with lots of challenges such as cytokine storm, how to find the specific antigen and limitation of microenvironment of tumor. In this review, we will discuss the research of CAR-T cell therapy for solid tumors of digestive system, and possible solutions and future direction.
Keywords:
Chimeric antigen receptor Solid tumor Antigen Cytokine release syndrome Cancer research Cell therapy Tumor microenvironment CAR T-cell therapy T cell Receptor Immunotherapy Medicine Immunology Cell Tumor cells Immune system Biology Cancer Internal medicine Biochemistry
Metrics
1
Cited By
0.50
FWCI (Field Weighted Citation Impact)
36
Refs
0.58
Citation Normalized Percentile
Is in top 1%
Is in top 10%
Citation History
Topics
CAR-T cell therapy research
Health Sciences → Medicine → Oncology
Biomedical Ethics and Regulation
Health Sciences → Medicine → Physiology
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