Basic fibroblast growth factor promotes human dental pulp stem cells cultured in 3D porous chitosan scaffolds to neural differentiation
Ke ZhengGuijuan FengJinlong ZhangJing XingDan HuangMin LianWei ZhangWen‐Li WuYingzi HuXiaohui LüXingmei Feng
Abstract
Chitosan scaffolds were non-cytotoxic to the survival of DPSCs, and chitosan scaffolds combined with bFGF facilitated the neural differentiation of DPSCs. The transplantation of DPSCs/chitosan-scaffold+bFGF might be a secure and effective method of treating SCI and other neuronal diseases.
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