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JOURNAL ARTICLE

Dendritic cells dictate responses to PD-L1 blockade cancer immunotherapy

Maud Mayoux Andreas Roller Vesna Pulko Stefano Sammicheli Stanford Chen Eva Sum Christian Jöst Marieke F. Fransen Regula B. Buser Marcin Kowanetz Karolin Rommel Ines Matos Sara Colombetti Anton Belousov Vaios Karanikas Ferry Ossendorp Priti S. Hegde Daniel S. Chen Pablo Umaña Mario Perro Christian Klein Wei Xu

Year: 2020 Journal: Science Translational Medicine Vol: 12 (534) Publisher: American Association for the Advancement of Science

DOI: 10.1126/scitranslmed.aav7431

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Abstract

DCs are critical cellular targets of PD-L1 blockade in cancer treatment.

Keywords:

CD80 Atezolizumab Blockade PD-L1 Immunotherapy Medicine Priming (agriculture) T cell Cancer Cancer immunotherapy Antibody Cancer research Immune system Blocking antibody Immune checkpoint Dendritic cell Immunology Receptor Nivolumab Biology Cytotoxic T cell Internal medicine CD40 In vitro

Metrics

359

Cited By

23.94

FWCI (Field Weighted Citation Impact)

29

Refs

1.00

Citation Normalized Percentile

Is in top 1%

Is in top 10%

Citation History

Topics

Cancer Immunotherapy and Biomarkers

Health Sciences → Medicine → Oncology

Immunotherapy and Immune Responses

Life Sciences → Immunology and Microbiology → Immunology

CAR-T cell therapy research

Health Sciences → Medicine → Oncology

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