JOURNAL ARTICLE

The Association of Phosphodiesterase 5 Inhibitor on Ischemia-Reperfusion Induced Kidney Injury in Rats.

Jong Kil NamJung Hee KimSung‐Woo ParkMoon Kee Chung

Year: 2020 Journal:   PubMed Vol: 17 (1)Pages: 91-96   Publisher: National Institutes of Health

Abstract

Tadalafil significantly promotes functional recovery after renal IR injury and effectively inhibits the induction of pro-inflammatory and inflammatory mediators. The results substantiate Tadalafil as a protective agent against IR-induced renal injury.

Keywords:
Medicine Tadalafil Creatinine Kidney cGMP-specific phosphodiesterase type 5 Internal medicine Renal function Endocrinology Phosphodiesterase inhibitor Reperfusion injury Pharmacology Ischemia Sildenafil

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0.39
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0.56
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Citation History

Topics

Phosphodiesterase function and regulation
Life Sciences →  Biochemistry, Genetics and Molecular Biology →  Molecular Biology
Adenosine and Purinergic Signaling
Life Sciences →  Biochemistry, Genetics and Molecular Biology →  Physiology
Neurological Complications and Syndromes
Health Sciences →  Medicine →  Psychiatry and Mental health

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