Targeted inhibition of ULK1 enhances daunorubicin sensitivity in acute myeloid leukemia
Abstract
These results revealed that pro-survival autophagy induced by ULK1 activation was one of the potential mechanisms of AML resistance to DNR. Targeting ULK1 selectively could be a promising therapeutic strategy to enhance sensitivity of DNR for AML therapy.
Metrics
Citation History
Topics
Related Documents
ULK1 inhibition as a targeted therapeutic strategy for FLT3-ITD-mutated acute myeloid leukemia
Doh Yu HwangJu-In EomJi Eun JangHoi-Kyung JeungHaerim ChungJin Seok KimJune‐Won CheongYoo Hong Min
Targeting PLZF Enhances Glucocorticoid Sensitivity in Acute Myeloid Leukemia
Azadeh HajmirzaLaura SimonJalila ChagraouiNadine MayotteJean-François SpinellaTara MacRaeBernhard LehnertzThierry BertomeuJasmin Coulombe‐HuntingtonGeneviève BoucherSébastien LemieuxMike TyersJosée HébertGuy Sauvageau
Additional file 1 of ULK1 inhibition as a targeted therapeutic strategy for FLT3-ITD-mutated acute myeloid leukemia
Doh Yu HwangJu-In EomJang, Ji EunHoi-Kyung JeungHaerim ChungKim, Jin SeokJune-Won CheongMin, Yoo Hong
Additional file 2 of ULK1 inhibition as a targeted therapeutic strategy for FLT3-ITD-mutated acute myeloid leukemia
Doh Yu HwangJu-In EomJang, Ji EunHoi-Kyung JeungHaerim ChungKim, Jin SeokJune-Won CheongMin, Yoo Hong