808 nm‐Light‐Excited Near‐Infrared Luminescent Lanthanide Metal–Organic Frameworks for Highly Sensitive Physiological Temperature Sensing

Abstract

Abstract Ongoing demand for accurate self‐calibrated noninvasive thermometers for micro‐/nano‐scale applications, particular biomedical diagnosis, is driving the development of temperature sensors. Here a new type of lanthanide metal–organic framework having near‐infrared absorption and near‐infrared emission features is presented, and it is based on efficient Nd 3+ ‐to‐Yb 3+ energy transfer in 808 nm photoexcitation. The results show that the ratiometric parameter of Nd 0.5 Yb 0.5 TPTC (TPTC= 1,1′:4′,1′′‐terphenyl]‐3,3′′,5,5′′‐tetracarboxylic acid) can deliver good exponential‐type luminescence response to temperature in the physiological regime (293–328 K) with high relative sensitivity and accurate temperature resolution, as well as good biocompatibility and chemical stability. Such lanthanide‐based materials are especially useful in biomedical applications.