CD151 promotes breast cancer metastasis by activating TGF-β1/Smad signaling pathway.

Zhao Sj; Zhao Hd; Li J; H Zhang; Gao Dt; QiYu WANG

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JOURNAL ARTICLE

CD151 promotes breast cancer metastasis by activating TGF-β1/Smad signaling pathway.

Zhao Sj Zhao Hd Li J H Zhang Gao Dt QiYu WANG

Year: 2018 Journal: PubMed Vol: 22 (21)Pages: 7314-7322 Publisher: National Institutes of Health

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Abstract

The expression of CD151 in BC was significantly increased, which was found evidently associated with BC stage, lymph node or distant metastasis, and poor prognosis. Meanwhile, CD151 may promote the proliferation and invasion of BC by regulating TGF-β1/Smad pathway.

Keywords:

Gene knockdown SMAD Cancer research Metastasis Vimentin Western blot Biology Gene silencing Transforming growth factor Cell growth Cancer Cell culture Immunology Immunohistochemistry Cell biology Gene

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Cancer Cells and Metastasis

Health Sciences → Medicine → Oncology

Cell Adhesion Molecules Research

Health Sciences → Medicine → Immunology and Allergy

Immune cells in cancer

Life Sciences → Immunology and Microbiology → Immunology

CD151 promotes breast cancer metastasis by activating TGF-β1/Smad signaling pathway.

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