JOURNAL ARTICLE

Sodium Alginate Based Mucoadhesive Hydrogels

M. Yu. GorshkovaI. F. VolkovaЛ. В. ВанчуговаИ. Л. ВалуевЛ. И. Валуев

Year: 2019 Journal:   Applied Biochemistry and Microbiology Vol: 55 (4)Pages: 371-374   Publisher: Pleiades Publishing

Abstract

The potential use of sodium-alginate hydrogels as mucoadhesive drug delivery carriers for intranasal application is studied. It is demonstrated that the drug release rate is dependent on the drug solubility in water, the drug concentration in the carrier, and the degree of alginate crosslinking.

Keywords:
Self-healing hydrogels Sodium alginate Drug delivery Drug Chemistry Solubility Nasal administration Drug carrier Pharmacology Sodium Polymer chemistry Organic chemistry Medicine

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12
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0.52
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Citation History

Topics

Advanced Drug Delivery Systems
Life Sciences →  Pharmacology, Toxicology and Pharmaceutics →  Pharmaceutical Science
Hydrogels: synthesis, properties, applications
Life Sciences →  Biochemistry, Genetics and Molecular Biology →  Molecular Medicine
Ocular Surface and Contact Lens
Health Sciences →  Medicine →  Public Health, Environmental and Occupational Health
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