Colorimetric and fluorescent dual-mode detection of microRNA based on duplex-specific nuclease assisted gold nanoparticle amplification

Jin Huang; Jingfang Shangguan; Qiuping Guo; Wenjie Ma; Huizhen Wang; Ruichen Jia; Zi Ye; Xiaoxiao He; Kemin Wang

doi:10.1039/c9an01013k

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Colorimetric and fluorescent dual-mode detection of microRNA based on duplex-specific nuclease assisted gold nanoparticle amplification

Jin Huang Jingfang Shangguan Qiuping Guo Wenjie Ma Huizhen Wang Ruichen Jia Zi Ye Xiaoxiao He Kemin Wang

Year: 2019 Journal: The Analyst Vol: 144 (16)Pages: 4917-4924 Publisher: Royal Society of Chemistry

DOI: 10.1039/c9an01013k

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Abstract

Colorimetric and fluorescent dual-mode detection of microRNA based on duplex-specific nuclease assisted gold nanoparticle amplification.

Keywords:

Nuclease Colloidal gold Fluorescence Duplex (building) Rolling circle replication DNA microRNA Nanotechnology Chemistry Biophysics Nanoparticle Materials science Biology Polymerase Biochemistry Gene Physics Optics

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Advanced biosensing and bioanalysis techniques

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

RNA Interference and Gene Delivery

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

MicroRNA in disease regulation

Life Sciences → Biochemistry, Genetics and Molecular Biology → Cancer Research

Colorimetric and fluorescent dual-mode detection of microRNA based on duplex-specific nuclease assisted gold nanoparticle amplification

Abstract

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