ChemInform Abstract: Alkylation of Adenine, Adenosine, and NAD+ with 1,3‐Propanesultone. Synthesis of N6‐(3‐Sulfonatopropyl)‐NAD+, a New NAD+ Derivative with Substantial Coenzyme Activity.

JOURNAL ARTICLE

Year: 1988 Journal: ChemInform Vol: 19 (38) Publisher: Wiley

DOI: 10.1002/chin.198838332

Abstract

Abstract The reaction of adenosine (I) with the sultone (II) gives the 1‐alkylation product (III), which is subsequently isomerized to (IV).

Keywords:

Chemistry NAD+ kinase Alkylation Adenosine Derivative (finance) Cofactor Stereochemistry Biochemistry Catalysis Enzyme

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