Reaction of 5-Substituted 2-Amino-2-oxazolines with Ethoxycarbonyl Isothiocyanate
Christian JarryIsabelle ForfarJ J Mueller ThomasJean Michel LégerMichel S. Laguerre
Abstract
&&&t -The reaction of 2-amino-2-oxazolines wilh ethoxycarbonyl isothiocyanate was found to give only 2,3,6,7-tetrahydro-4Hoxazolo[3,2-a]-l,3,5-triazin-2-one-4-thiones, the structure of which was confirmed by X-ray crystallographic analysis.The direction of attack seems to be related to the more potent nuclwphilic character of the endo nitrogen atom in 2-amino-2-oxazolines.In basic conditions the oxazoline ring can be easily hydrolyzed leading to 1-substituted 135-triazin-2,4-dione-6-thione.
Metrics
Topics
Related Documents
ChemInform Abstract: Reaction of 5‐Substituted 2‐Amino‐2‐oxazolines with Ethoxycarbonyl Isothiocyanate.
C. JarryIsabelle ForfarJoice ThomasJ.-M. LégerMichel S. Laguerre
Studies on Organic Sulfur Compounds. IX. The Reaction of Ethoxycarbonyl Isothiocyanate with 4, 5-Substituted 2-Aminothiazoles
Mitsuo NaganoTakashi MatsuiJunzo TobitsukaK. OYAMADA
2-SUBSTITUTED-5-METHYL-2-OXAZOLINES
Samuel P. McManusJohn T. CarrollP. M. GrohseCharles U. Pittman
ChemInform Abstract: Reaction of 5‐Substituted‐2‐amino‐2‐oxazolines with Ethoxycarbonyl Isocyanate. A Route to 2,3,6,7‐Tetrahydro‐4H‐oxazolo(3,2‐a)‐1,3,5‐ triazine‐2,4‐diones
O.-S. AdetchessiD. DesorIsabelle ForfarC. JarryJean‐Michel LégerMichel S. LaguerreA. Carpy