One-Pot Synthesis of Indoles from Ketones and Hydrazines under Mild Reaction Conditions

Okiko Miyata; Yasuo Kimura; Takeaki Naito

doi:10.1055/s-2001-16756

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One-Pot Synthesis of Indoles from Ketones and Hydrazines under Mild Reaction Conditions

Okiko Miyata Yasuo Kimura Takeaki Naito

Year: 2001 Journal: Synthesis Vol: 2001 (11)Pages: 1635-1638 Publisher: Thieme Medical Publishers (Germany)

DOI: 10.1055/s-2001-16756

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Abstract

A facile one-pot method is presented for the synthesis of indoles via condensation of ketone with hydrazine followed by acylation and rearrangement. This convenient synthetic method provides an easy and simple access to indoles.

Keywords:

Chemistry Ketone Acylation Hydrazine (antidepressant) Organic chemistry Condensation Reaction conditions Combinatorial chemistry Condensation reaction Catalysis

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Asymmetric Hydrogenation and Catalysis

Physical Sciences → Chemistry → Inorganic Chemistry

Chemical Synthesis and Reactions

Physical Sciences → Chemistry → Organic Chemistry

Nanomaterials for catalytic reactions

Physical Sciences → Chemistry → Organic Chemistry

One-Pot Synthesis of Indoles from Ketones and Hydrazines under Mild Reaction Conditions

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