JOURNAL ARTICLE
Transforming growth factor-β stimulates nerve growth factor production in osteoarthritic synovium
Shotaro TakanoKentaro UchidaMakoto ItakuraDai IwaseJun AikawaGen InoueManabu MukaiMasayuki MiyagiKosuke MurataHiroyuki SekiguchiMasashi Takaso
Year: 2019 Journal: BMC Musculoskeletal Disorders Vol: 20 (1)Pages: 204-204 Publisher: BioMed Central
Abstract
TGF-β regulates NGF production via the TGF-β/ALK5 signaling pathway in osteoarthritic synovium. This effect may partially occur through inhibition of the TAK1/p38 pathway in the SYT of KOA patients.
Keywords:
Medicine Sports medicine Nerve growth factor Rheumatology Transforming growth factor Orthopedic surgery Growth factor Internal medicine Osteoarthritis Pathology Surgery Receptor
Metrics
20
Cited By
3.05
FWCI (Field Weighted Citation Impact)
29
Refs
0.88
Citation Normalized Percentile
Is in top 1%
Is in top 10%
Citation History
Topics
Osteoarthritis Treatment and Mechanisms
Health Sciences → Medicine → Rheumatology
Tendon Structure and Treatment
Health Sciences → Medicine → Orthopedics and Sports Medicine
Spine and Intervertebral Disc Pathology
Health Sciences → Medicine → Pathology and Forensic Medicine
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