Argentination of Fluoroform: Preparation of a Stable AgCF₃ Solution with Diverse Reactivities

Abstract

Abstract The transformation of a large‐volume industrial by‐product and stable greenhouse gas fluoroform (HCF 3 ) to useful products has recently received significant attention. Now, a simple and scalable preparation of AgCF 3 by treatment of HCF 3 with t ‐BuOK and AgOAc is disclosed. The reactivity of the HCF 3 ‐derived AgCF 3 has been demonstrated by hydrotrifluoromethylation of alkenes and C−H trifluoromethylation of (hetero)arenes. This work not only provides a new avenue for the utilization of HCF 3 , but also presents a reliable and easy‐to‐execute synthesis of the relatively stable AgCF 3 solution.