Antimicrobial dressings for treating local infection in patients with diabetic foot ulcers

Abstract

Infection in diabetic foot ulcers puts patients at risk of hospitalisation and amputation. Microorganisms populate chronic wounds on a continuum from non-pathological surface contamination to local infection and/or deep compartment infection. Early diagnosis of infection based on relevant clinical signs and symptoms is critical, and treatment reflects the degree of infection. Treatment of superficial infection can involve dressings impregnated with antimicrobial agents. Dressing choice recommendations in clinical practice guidelines, however, are primarily used to ensure optimal moisture balance is achieved and facilitate autolytic debridement. Current evidence, although weak, favours antimicrobial dressings. Future research should be more robust and adequately powered.