JOURNAL ARTICLE
TUG1 knockdown enhances adriamycin cytotoxicity by inhibiting glycolysis in adriamycin-resistant acute myeloid leukemia HL60/ADR cells
Li ChenHongmian ZhaoChao WangNing Hu
Year: 2019 Journal: RSC Advances Vol: 9 (19)Pages: 10897-10904 Publisher: Royal Society of Chemistry
Abstract
Taurine-upregulated gene 1 (TUG1) has been reported as an oncogenic long non-coding RNA (lncRNA) in acute myeloid leukemia (AML).
Keywords:
Protein kinase B Gene knockdown Myeloid leukemia Anaerobic glycolysis PKM2 Cytotoxicity HL60 Apoptosis Chemistry Glycolysis Cancer research MTT assay PI3K/AKT/mTOR pathway Pyruvate kinase Molecular biology Biology Biochemistry Metabolism In vitro
Metrics
18
Cited By
0.27
FWCI (Field Weighted Citation Impact)
35
Refs
0.49
Citation Normalized Percentile
Is in top 1%
Is in top 10%
Citation History
Topics
Cancer-related molecular mechanisms research
Life Sciences → Biochemistry, Genetics and Molecular Biology → Cancer Research
RNA modifications and cancer
Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology
RNA Research and Splicing
Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology
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