Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism

Ji‐Young Lee; Ali E. Yesilkanal; Joseph Wynne; Casey Frankenberger; Juan Liu; Jielin Yan; Mohamad Elbaz; Daniel C. Rabe; Felicia Rustandy; Payal Tiwari; Philip Achacoso; Peter C. Hart; Christie Kang; Sydney M. Sanderson; Jorge Andrade; Daniel K. Nomura; Marcelo G. Bonini; Jason W. Locasale; Marsha Rich Rosner

doi:10.1038/s41586-019-1005-x

JOURNAL ARTICLE

Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism

Ji‐Young Lee Ali E. Yesilkanal Joseph Wynne Casey Frankenberger Juan Liu Jielin Yan Mohamad Elbaz Daniel C. Rabe Felicia Rustandy Payal Tiwari Philip Achacoso Peter C. Hart Christie Kang Sydney M. Sanderson Jorge Andrade Daniel K. Nomura Marcelo G. Bonini Jason W. Locasale Marsha Rich Rosner

Year: 2019 Journal: Nature Vol: 568 (7751)Pages: 254-258 Publisher: Nature Portfolio

DOI: 10.1038/s41586-019-1005-x

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Keywords:

Cancer research Small hairpin RNA Biology Citric acid cycle Mitochondrion Transcription factor Breast cancer Cancer cell Triple-negative breast cancer Cancer Gene Cell biology Metabolism Biochemistry Gene knockdown Genetics

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398

Cited By

18.55

FWCI (Field Weighted Citation Impact)

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0.99

Citation Normalized Percentile

Is in top 1%

Is in top 10%

Citation History

Topics

Epigenetics and DNA Methylation

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

Mitochondrial Function and Pathology

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

Cancer, Hypoxia, and Metabolism

Life Sciences → Biochemistry, Genetics and Molecular Biology → Cancer Research

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DISSERTATION

Targeting cancer metabolism for breast cancer therapy

Ramon Sun Chang

University: ANU Open Research (Australian National University) Year: 2010