Cover Feature: Virus‐Based Nanomotors for Cargo Delivery (ChemNanoMat 2/2019)

Abstract

Self-propelled nanomotors based on virus capsids were designed by covering one hemisphere with a platinum layer to promote motion in the presence of hydrogen peroxide. The Janus viral nanomotors can carry and deliver chemotherapeutic drugs, and they are able to internalize into cancer cells without any functionalization. The therapeutic payload is released by a pH-driven delivery action of the nanomotor. This first proof of concept of a self-propelled virus-like nanoparticle paves the way to diverse biomedical applications. More information can be found in the Full Paper by Joseph Wang, Rafael Vazquez-Duhalt et al. on page 194 in Issue 2, 2019 (DOI: 10.1002/cnma.201800403).