Highly sensitive glucose detection using Au Nanoparticles based fiber optic SPR sensor

Abstract

A highly sensitive surface plasmon resonance (SPR) sensor for glucose detection has been proposed by using self-assembled p-mercaptophenylboronic acid (PMBA) monolayer on Au coated tilted fiber Bragg grating. Au nanoparticles (Au NPs) were modified with 2-aminoethanethiol (AET) and PMBA for signal amplification. It exhibits high sensitivity and selective response to glucose over fructose and galactose within the range of 1μM–500μM and the sensitivity is up to 2.61dB/μM.