JOURNAL ARTICLE

Preliminary Experimental Characterization of Gelatin-Based Tissue-Mimicking Materials for Realistic Breast Phantoms aimed at Microwave Applications

Abstract

Breast cancer is the most aggressive and common cause of death among women around the world, and an early diagnosis is fundamental to increase the survival chances. Microwave and mm-wave imaging systems have been recently proposed as a possible technique for cancer detection, on the grounds of the different dielectric permittivity between healthy and neoplastic tissues. To support the experimental development of such systems, phantoms able to mimic the different dielectric permittivity are required. In addition, the possibility to provide, at the same time, mechanical properties similar to those of real tissues would be beneficial to deliver phantoms as realistic as possible. In this paper, two simple and easy-to-produce mixtures able to mimic the dielectric properties of neoplastic breast tissue are presented; their dielectric properties are compared to the ones derived from human neoplastic ex-vivo samples and their mechanical properties are tested. In particular, two different percentages of gelling material are used and both the dielectric and mechanical material properties are measured, demonstrating the possibility to tune the Young's module of the samples.

Keywords:
Dielectric Microwave Permittivity Microwave imaging Materials science Breast cancer Human breast Gelatin Characterization (materials science) Biomedical engineering Dielectric permittivity Biological materials Biological tissue Cancer Computer science Optoelectronics Nanotechnology Medicine Chemistry Telecommunications

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Citation History

Topics

Microwave Imaging and Scattering Analysis
Physical Sciences →  Engineering →  Biomedical Engineering
Ultrasonics and Acoustic Wave Propagation
Physical Sciences →  Engineering →  Mechanics of Materials
Microwave and Dielectric Measurement Techniques
Physical Sciences →  Engineering →  Electrical and Electronic Engineering
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