JOURNAL ARTICLE
Sensitive and label-free discrimination of 5-hydroxymethylcytosine and 5-methylcytosine in DNA by ligation-mediated rolling circle amplification
Ziyue WangMeng WangYan ZhangChun‐yang Zhang
Year: 2018 Journal: Chemical Communications Vol: 54 (62)Pages: 8602-8605 Publisher: Royal Society of Chemistry
Abstract
We develop a label-free fluorescence method for sensitive discrimination of 5-hydroxymethylcytosine (5hmC) and 5-methylcytosine (5mC) by ligation-mediated rolling circle amplification.
Keywords:
5-Hydroxymethylcytosine 5-Methylcytosine DNA Rolling circle replication Ligation Chemistry Biology Molecular biology DNA methylation Biochemistry DNA polymerase Gene
Metrics
26
Cited By
1.82
FWCI (Field Weighted Citation Impact)
33
Refs
0.83
Citation Normalized Percentile
Is in top 1%
Is in top 10%
Citation History
Topics
DNA and Nucleic Acid Chemistry
Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology
Epigenetics and DNA Methylation
Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology
Genomics and Chromatin Dynamics
Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology
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