Phosphorus-Containing Aminocarboxylic Acids: XV. α,ω-Diamino-ω,ω-diphosphonoalkylcarboxylic Acids

Abstract

A general method for the synthesis of phosphonic aminocarboxylic acids combining aminodiphosphonic and amino acid functions in one molecule was developed. Amino acids of a new type are AP-acids analogs, which are ligands of glutamate receptors that determine the processes of information transmission and processing in the central nervous system, and can also be promising compounds as new components of radiopharmaceuticals.