Inhibition of PI3K/Akt/mTOR pathway by apigenin induces apoptosis and autophagy in hepatocellular carcinoma cells

Jiali Yang; Cuicui Pi; Guanghui Wang

doi:10.1016/j.biopha.2018.04.072

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Inhibition of PI3K/Akt/mTOR pathway by apigenin induces apoptosis and autophagy in hepatocellular carcinoma cells

Jiali Yang Cuicui Pi Guanghui Wang

Year: 2018 Journal: Biomedicine & Pharmacotherapy Vol: 103 Pages: 699-707 Publisher: Elsevier BV

DOI: 10.1016/j.biopha.2018.04.072

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Keywords:

Apigenin Autophagy PI3K/AKT/mTOR pathway Apoptosis Protein kinase B Programmed cell death Chemistry Cell growth Cancer research Signal transduction Cell biology Pharmacology Biology Biochemistry Flavonoid Antioxidant

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Autophagy in Disease and Therapy

Health Sciences → Medicine → Epidemiology

Flavonoids in Medical Research

Health Sciences → Medicine → Pharmacology

Bioactive Natural Diterpenoids Research

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

Inhibition of PI3K/Akt/mTOR pathway by apigenin induces apoptosis and autophagy in hepatocellular carcinoma cells

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