Colorimetric Detection of Hg²⁺ Based on Enhancement of Peroxidase‐like Activity of Chitosan‐Gold Nanoparticles

Abstract

Hg 2+ is a serious environmental contaminant that can cause severe damage to the immune and nervous systems, and Hg 2+ monitoring is critical. Herein, we report a novel, simple, and sensitive Hg 2+ sensor based on the enhanced peroxidase‐like activity of chitosan–gold nanoparticles (CS‐AuNPs). The peroxidase‐like activity of the CS‐AuNPs can be markedly enhanced by Hg 2+ as seen by the deeper color and increased absorbance at 652 nm. This improved catalytic ability was used to develop a sensitive and selective colorimetric sensor for Hg 2+ detection. The limit of detection via the absorption spectra is as low as 0.02 μM. The mechanism underlying the enhanced catalytic ability is discussed. This approach is label‐free, simple, and offers detection with the naked eye. Thus, it has potential applications for the detection of Hg 2+ in environmental and food samples.