FEATURES OF ACUTE MYOCARDIAL INFARCTION IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Abstract

The aim of the study is to investigate the clinical features of acute myocardial infarction (AMI) manifestation in patients with COPD. 46 male patients with AMI and COPD comorbidity were examined. The first group (26 people) included the patients who had myocardial infarction with ST elevation and COPD. The second group (20 people) had AMI with ST elevation and no COPD anamnesis. The examination included electrocardiography (ECG), echocardiography, coronary angiography, spirography, arterial blood gases measurement. The following results were obtained: in a case of COPD and AMI comorbidity a smoking is the common risk factor. Patients, who had COPD, often demonstrate an asthmatic variant of AMI manifestation, the greater number of complications such as fatal arrhythmia, pulmonary edema, and clinical death. The presence of COPD has a negative influence on AMI course: in patients with COPD during the development of AMI, a higher level of markers of systemic inflammation is detected, a greater severity of hypoxemia indices, which in turn reduces the myocardium contractility in the early recovery period. The patients with COPD and AMI comorbidity have a multivessel lesion of the coronary bed, that can make the further prognosis worse.